Protective potency of Meristotropis xanthioides against nephrotoxicity in a rat model along with its antioxidant and antibacterial activities
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چکیده
منابع مشابه
Protective Effect of Safranal against Gentamicin-Induced Nephrotoxicity in Rat
Gentamicin is an important aminoglycoside antibiotic. However its use is limited to serious and life threatening gram negative infections, because of its high nephrotoxicity potential in patients. There are reports that safranal, the active ingredient of saffron with antioxidant properties, exerts protective effect against ischemic injuries occurred by certain nephrotoxins including gentamicin....
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Background: Hexachlorobutadiene (HCBD) is a potent nephrotoxin in rodents, which can cause degeneration, necrosis and regeneration in renal tubular epithelial cells. It has been shown that safranal, the active ingredient of saffron, has a protective effect against ischemic injuries. The aim of this study was to examine the protective effect of safranal against HCBD-induced nephrotoxicity in rat...
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Background: Hexachlorobutadiene (HCBD), a potent nephrotoxin can cause degeneration and necrosis in renal tubular epithelial cells in rodents. Its toxicity is due to conjugation with glutathione to form the related cysteine conjugate. This metabolite is then taken up by the kidney and cleared through renal tubular epithelial cells as a reactive thiol derivative by the enzyme β-lyase. Objective:...
متن کاملprotective effect of safranal against hexachlorobutadiene-induced nephrotoxicity in rat
background: hexachlorobutadiene (hcbd) is a potent nephrotoxin in rodents, which can cause degeneration, necrosis and regeneration in renal tubular epithelial cells. it has been shown that safranal, the active ingredient of saffron, has a protective effect against ischemic injuries. the aim of this study was to examine the protective effect of safranal against hcbd-induced nephrotoxicity in rat...
متن کاملprotective effect of safranal against gentamicin-induced nephrotoxicity in rat
gentamicin is an important aminoglycoside antibiotic. however its use is limited to serious and life threatening gram negative infections, because of its high nephrotoxicity potential in patients. there are reports that safranal, the active ingredient of saffron with antioxidant properties, exerts protective effect against ischemic injuries occurred by certain nephrotoxins including gentamicin....
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Medicine
سال: 2017
ISSN: 1995-7645
DOI: 10.1016/j.apjtm.2017.09.007